PARP inhibitor UPF 1069, Purity ≥98%

Synonym: 1048371-03-4; UPF 1069; UPF-1069; 5-(2-oxo-2-Phenylethoxy)isoquinolin-1(2H)-one; 5-Phenacyloxy-2H-isoquinolin-1-one; PARP inhibitor

MDL: MFCD14051631
CAS Number: 1048371-03-4
Compound CID: 25015515

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

UPF 1069, soluble in DMSO and insoluble in ethanol and water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks. It targets PARP2 and PARP1.

Molecular Weight

279.29

Molecular Formula

C₁₇H₁₃NO₃

Targets

PARP2: 0.3 μM; PARP1: 8.0 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 54 mg/mL (193.34 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

UPF 1069 can be used to investigate its function as a PARP inhibitor in neuroprotection.