PARP inhibitor WIKI4, Purity ≥98%

Synonym: 838818-26-1; WIKI4; WIKI-4; 2-[3-[[4-(4-Methoxyphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]propyl]benzo[de]isoquinoline-1,3-dione; PARP inhibitor

MDL: MFCD05885187
CAS Number: 838818-26-1
Compound CID: 2984337

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

WIKI4, soluble in warmed DMSO and insoluble in water and ethanol, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks. It targets TNKS2.

Molecular Weight

521.59

Targets

TNKS2: 15 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 7 mg/mL (13.42 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

WIKI4 can be used to explore tankyrase inhibition and its effects on Wnt signaling.