Properties
Description
WIKI4, soluble in warmed DMSO and insoluble in water and ethanol, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks. It targets TNKS2.
Solubility
Warmed DMSO: 7 mg/mL (13.42 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
WIKI4 can be used to explore tankyrase inhibition and its effects on Wnt signaling.
