PARP inhibitor XMD16-5, Purity ≥98%

Synonym: 1345098-78-3; XMD16-5; 2-[4-(4-Hydroxypiperidin-1-yl)anilino]-11-methyl-5H-pyrimido[4,5-b][1,4]benzodiazepin-6-one; PARP inhibitor

CAS Number: 1345098-78-3
Compound CID: 57340666

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

XMD16-5, soluble in DMSO and ethanol and insoluble in water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks.

Molecular Weight

416.48

Molecular Formula

C₂₃H₂₄N₆O₂

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 81 mg/mL (194.48 mM); Water: Insoluble; Ethanol: 5 mg/mL (12 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

XMD16-5 can be used to explore BMK1 inhibition and its effects on cancer cell proliferation.