PARP inhibitor XMD8-87, Purity ≥98%

Synonym: 1234480-46-6; XMD8-87; ACK1-B19; 5,11-Dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one; PARP inhibitor

MDL: MFCD30742941
CAS Number: 1234480-46-6
Compound CID: 53322923

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

XMD8-87, soluble in DMSO and ethanol and insoluble in water, binds to the PARP enzyme's active site, preventing it from repairing single-strand DNA breaks.

Molecular Weight

445.5

Molecular Formula

C₂₄H₂₇N₇O₂

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 57 mg/mL (127.93 mM); Water: Insoluble; Ethanol: 4 mg/mL (8.98 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

XMD8-87 can be used to study the inhibition of BMK1 and its role in cellular signaling.