Properties
Description
Apremilast, soluble in DMSO and insoluble in water and ethanol, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting PDE. It targets the PDE4.
Molecular Formula
C22H24N2O7S
Targets
PDE4: 74 nM (IC50)
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 85 mg/mL (184.58 mM); Water: insoluble; Ethanol: insoluble; In vivo: 0.5% CMC + 0.25% Tween 80, 28 mg/mL
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
Apremilast is a metabolism inhibitor that plays a key role in reducing inflammation and improving symptoms in these chronic conditions.
Storage
Store at -20ºC, and keep desiccated.
