PDE inhibitor, Icariin, Purity ≥98%

Synonym: 489-32-7; Ieariline; 5-Hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one

MDL: MFCD00210516
CAS Number: 489-32-7
Compound CID: 5318997

Product Size

50 mg; 100 mg; 250 mg; 500 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Icariin, soluble in DMSO and insoluble in water and ethanol, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting PDE. It targets the PDE5.

Molecular Weight

676.7

Molecular Formula

C₃₃H₄₀O₁₅

Targets

PDE5: 0.432 μM

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 46 mg/mL (67.98 mM); Water: insoluble; Ethanol: insoluble

Stability

In its lyophilized form, the chemical remains stable for 36 months.

Quality Level

Research grade

Applications

Icariin is a metabolism inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of osteoporosis, improving sexual function, and offering cardiovascular protection.

Storage

Store at -20ºC, and keep desiccated.