PDE inhibitor, ITI214 free base, Purity ≥98%

Synonym: 1160521-50-5; ITI-214; ITI 214; (11R,15S)-5-Anilino-4-[[4-(6-fluoropyridin-2-yl)phenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one; PDE inhibitor

CAS Number: 1160521-50-5
Compound CID: 42639643

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ITI214 free base is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting PDE. The molecular weight of the compound is 507.56, and its molecular formula is C₂₉H₂₆FN₇O. It targets the PDE1, PDE1A, PDE1B and PDE1C.

Molecular Weight

507.56

Molecular Formula

C₂₉H₂₆FN₇O

Targets

PDE1

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Identity

Confirmed by NMR/HPLC/MS.

Applications

ITI214 free base can be studied extensively for its potential therapeutic applications in the treatment of heart failure and neurodegenerative diseases by modulating cyclic AMP and cyclic GMP levels.