PDE inhibitor, PF-8380, Purity ≥98%

Synonym: 1144035-53-9; PF 8380; PF8380; (3,5-Dichlorophenyl)methyl 4-[3-oxo-3-(2-oxo-3H-1,3-benzoxazol-6-yl)propyl]piperazine-1-carboxylate

MDL: MFCD20527274
CAS Number: 1144035-53-9
Compound CID: 25265312

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PF-8380, soluble in DMSO and insoluble in water and ethanol, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting PDE. It targets the Autotaxin.

Molecular Weight

478.33

Molecular Formula

C₂₂H₂₁Cl₂N₃O₅

Targets

Autotaxin: 2.8 nM

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 89 mg/mL (186.06 mM); Water: insoluble; Ethanol: insoluble; In vivo: 1% cmc-na, 14 mg/mL

Stability

In its lyophilized form, the chemical remains stable for 36 months.

Quality Level

Research grade

Applications

PF-8380 is a metabolism inhibitor that can be used for its ability to enhance cognitive function and memory.

Storage

Store at -20ºC, and keep desiccated.