PDE inhibitor, Tadalafil, Purity ≥98%

Synonym: 171596-29-5; Adcirca; Cialis; (2R,8R)-2-(1,3-Benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione

MDL: MFCD07771966
CAS Number: 171596-29-5
Compound CID: 110635

Product Size

50 mg; 100 mg; 250 mg; 500 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Tadalafil, soluble in DMSO and insoluble in water and ethanol, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting PDE. It targets the PDE5 (cell-free assay).

Molecular Weight

389.4

Molecular Formula

C₂₂H₁₉N₃O₄

Targets

PDE5 (Cell-free assay): 1.8 nM

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 70 mg/mL (179.76 mM); Water: insoluble; Ethanol: insoluble; In vivo: 30% propylene glycol, 5% Tween 80, 65% D5W, 28 mg/mL

Applications

Tadalafil is a metabolism inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of erectile dysfunction and benign prostatic hyperplasia (BPH).