PDGFR inhibitor AG1295, Purity ≥98%

Synonym: 71897-07-9; PDGFR inhibitor; AG-1295; AG 1295; NSC 380341; Tyrphostin AG 1295

CAS Number: 71897-07-9
Compound CID: 2048

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AG1295 blocks the activity of platelet-derived growth factor receptors (PDGFR), which play a crucial role in cell growth, angiogenesis, and tissue. It targets c-Kit (D816H), c-Kit (D816V), c-Kit (V560G), c-Kit(V654A), PDGFRα(D842V), and PDGFRα(V561D).

Molecular Weight

234.3

Molecular Formula

C₁₆H₁₄N₂

Targets

c-Kit (D816H): 10 nM; c-Kit (D816V): 950 nM; c-Kit (V560G): 34 nM; c-Kit (V654A): 127 nM; PDGFRα (D842V): 81 nM; PDGFRα (V561D): 40 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

AG1295 serves as a PDGFR inhibitor, aiding research on targeting cancer cell growth and tumor angiogenesis.