PDGFR inhibitor GZD856, Purity ≥98%

Synonym: 1257628-64-0; PDGFR inhibitor; GZD 856; GZD-856

CAS Number: 1257628-64-0
Compound CID: 51037822

Product Size

1 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GZD856 blocks the activity of platelet-derived growth factor receptors (PDGFR), which play a crucial role in cell growth, angiogenesis, and tissue. It targets Bcr-Abl, Bcr-AblT315I, PDGFRα, and PDGFRβ.

Molecular Weight

532.56

Molecular Formula

C₂₉H₂₇F₃N₆O

Targets

Bcr-Abl: 19.9 nM; Bcr-AblT315I: 15.4 nM; PDGFRα: 68.6 nM; PDGFRβ: 136.6 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

GZD856 acts as a PDGFR inhibitor, facilitating research in pathological conditions involving aberrant PDGFR signaling.