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PDGFR inhibitor Ki8751, Purity ≥98%

Cat. No.: X24-06-ZQ130

PDGFR inhibitor Ki8751, Purity ≥98%

Synonym: 228559-41-9; PDGFR inhibitor; Ki-8751

  • MDL: MFCD09971092
  • CAS Number: 228559-41-9
  • Compound CID: 11317348
Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
Ki8751, soluble in DMSO and insoluble in ethanol and water, blocks the activity of platelet-derived growth factor receptors (PDGFR), which play a crucial role in cell growth, angiogenesis, and tissue. It targets c-Kit, PDGFRα, EGFR, FGFR2, HGFR, Insulin receptor, and VEGFR2.
Molecular Weight
469.4
Molecular Formula
C24H18F3N3O4
Targets
c-Kit: 40 nM; PDGFRα: 67 nM; EGFR: >10 μM; FGFR2: 170 nM; HGFR: >10 μM; Insulin receptor: >10 μM; VEGFR2: 0.9 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 46 mg/mL (97.99 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Ki8751 is used as a PDGFR inhibitor to facilitate research on therapies that impede cancer growth via PDGFR pathways.
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