PDGFR inhibitor PHA 291639, Purity ≥98%

Synonym: 356068-94-5; PDGFR inhibitor; PHA 291639; SU 11654; PHA-291639; SU-11654; PHA291639; SU11654

MDL: MFCD16038046
CAS Number: 356068-94-5
Compound CID: 5329106

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

PHA 291639 blocks the activity of platelet-derived growth factor receptors (PDGFR), which play a crucial role in cell growth, angiogenesis, and tissue. It targets Flk-1 and PDGFRβ.

Molecular Weight

396.46

Molecular Formula

C₂₂H₂₅FN₄O₂

Targets

Flk-1: 6 nM (Ki); PDGFRβ: 5 nM (Ki)

Form

Lyophilized powder

Purity

Identity

Confirmed by NMR/HPLC/MS.

Applications

PHA 291639 acts as a PDGFR inhibitor and is used in studies investigating the interruption of signal pathways involved in oncogenesis.