PDGFR inhibitor Sunitinib, Purity ≥98%

Synonym: 557795-19-4; PDGFR inhibitor; SU 11248; SU11248; SU-11248

MDL: MFCD09260778
CAS Number: 557795-19-4
Compound CID: 5329102

Product Size

100 mg; 500 mg

Price

Datasheet

MSDS

Properties

Description

Sunitinib, soluble in warmed DMSO and insoluble in water and ethanol, blocks the activity of platelet-derived growth factor receptors (PDGFR), which play a crucial role in cell growth, angiogenesis, and tissue. It targets PDGFRβ and VEGFR2.

Molecular Weight

398.47

Molecular Formula

C₂₂H₂₇FN₄O₂

Targets

PDGFRβ: 2 nM; VEGFR2: 80 nM

Form

Lyophilized powder

Purity

Solubility

Warmed DMSO: 23 mg/mL (57.71 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Sunitinib is used to inhibit PDGFR (Platelet-Derived Growth Factor Receptor), thereby playing a role in researching angiogenesis and cancer-related cellular proliferation.