PDK1 inhibitor OSU-03012, Purity ≥98%

Synonym: 742112-33-0; OSU-03012; AR-12; PDK1 inhibitor AR-12; OSU 03012; PDK1 inhibitor

CAS Number: 742112-33-0
Compound CID: 10027278

Product Size

5 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

OSU-03012, soluble in DMSO and insoluble in ethanol and water, is a potent PDK1 inhibitor that blocks PDK1/Akt signaling in tumor cells. It targets PDK-1.

Molecular Weight

460.2

Molecular Formula

C₂₆H₁₉F₃N₄O

Targets

PDK-1: 5 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 10 mg/mL (21.71 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

OSU-03012 can be used to inhibit PDK1, allowing studies on its role in cancer cell survival and apoptosis.