Properties
Description
TEPP-46, soluble in DMSO and insoluble in ethanol and water, is a potent PDK1 inhibitor that blocks PDK1/Akt signaling in tumor cells.
Molecular Formula
C17H16N4O2S2
Solubility
DMSO: 73 mg/mL (195.99 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
TEPP-46 can be used to activate pyruvate kinase M2 (PKM2), providing insights into cancer metabolism.
