PERK inhibitor GSK2656157, Purity ≥98%

Synonym: 1337532-29-2; GSK2656157; GSK-2656157; 1-(5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoroindolin-1-yl)-2-(6-methylpyridin-2-yl)ethanone; PERK inhibitor

MDL: MFCD27997885
CAS Number: 1337532-29-2
Compound CID: 53469059

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK2656157, soluble in DMSO and insoluble in ethanol and water, disrupts UPR pathway, potentially affecting apoptosis through various downstream effects. It targets PERK.

Molecular Weight

416.45

Molecular Formula

C₂₃H₂₁FN₆O

Targets

PERK: 0.9 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 28 mg/mL (67.23 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

GSK2656157 can be utilized to explore PERK inhibition and its role in tumor growth and survival.

Storage

Store at -20ºC.