Cat. No.: X23-10-ZQ157
PERK inhibitor Salubrinal, Purity ≥98%
Synonym: 405060-95-9; Salubrinal; J8PSF5Z8KJ; N-(2,2,2-Trichloro-1-(3-(quinolin-8-yl)thioureido)ethyl)cinnamamide; (E)-N-(2,2,2-Trichloro-1-(3-(quinolin-8-yl)thioureido)ethyl)cinnamamide; 3-Phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-2-propenamide; PERK inhibitor
- MDL: MFCD00548612
- CAS Number: 405060-95-9
- Compound CID: 5717801
Product Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
Salubrinal, soluble in DMSO and ethanol and insoluble in water, disrupts UPR pathway, potentially affecting apoptosis through various downstream effects. It targets eIF2α.
Molecular Formula
C21H17N4OSCl3
Solubility
DMSO: 86 mg/mL (179.23 mM); Water: Insoluble; Ethanol: 2 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Salubrinal can be employed to investigate the ER stress pathway and its implications in treating diseases such as cancer.
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