Properties
Description
PF-5274857, soluble in DMSO and water, and insoluble in ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets smoothened.
Molecular Formula
C20H25ClN4O3S
Targets
Smoothened: 5.8 nM; Smoothened: 4.6 nM (Ki)
Solubility
DMSO: 83 mg/mL (189.95 mM); Water: 83 mg/mL (189.95 mM); Ethanol: insoluble
Applications
PF-5274857 can be studied for its effect on specific molecular targets or biological pathways.
