PFKFB3 inhibitor, 3PO, Purity ≥98%

Synonym: 13309-08-5; 18550-98-6; 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one; (E)-3PO; (E)-3-Pyridin-3-yl-1-pyridin-4-ylprop-2-en-1-one; (E)-3-Pyridin-3-yl-1-pyridin-4-ylprop-2-en-1-one; PFKFB3 inhibitor

CAS Number: 13309-08-5; 18550-98-6
Compound CID: 5720233

Product Size

25 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

3PO, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting PFKFB3. The molecular weight of the compound is 210.24, and its molecular formula is C₁₃H₁₀N₂O.

Molecular Weight

210.24

Molecular Formula

C₁₃H₁₀N₂O

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 39 mg/mL (185.51 mM); Water: insoluble; Ethanol: 39 mg/mL; In vivo: 2% DMSO + 40% PEG 300 + 2% Tween 80 + ddH₂O, 1 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

3PO displays the significant potential to act as an effective inhibitor of AMP-activated protein kinase (AMPK), impacting metabolic pathways related to energy regulation.