Properties
Description
Phenprocoumon, soluble in DMSO and ethanol and insoluble in water, is a vitamin K antagonist that inhibits coagulation by blocking synthesis of coagulation factors II, VII, IX and X. The molecular weight of the compound is 280.3, and its molecular formula is C18H16O3.
Molecular Formula
C18H16O3
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 55 mg/mL (196.2 mM); Water: insoluble; Ethanol: 55 mg/mL (196.2 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Phenprocoumon can be used for its ability to inhibit the vitamin K epoxide reductase complex, which is critical for the synthesis of clotting factors II, VII, IX, and X.