Properties
Description
Phenylbiguanide, soluble in DMSO, ethanol and water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT3 receptor.
Molecular Formula
C8H11N5
Targets
5-HT3 receptor: 3 μM (EC50)
Solubility
DMSO: 34 mg/mL (191.86 mM); Water: 34 mg/mL (191.86 mM); Ethanol: 16 mg/mL
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Phenylbiguanide can be used for research on gut motility, visceral sensation, and other aspects of gastrointestinal function.
Storage
Store at -20°C, and keep desiccated.