Properties
Description
Phenylbiguanide, soluble in DMSO, ethanol and water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT3 receptor.
Molecular Formula
C8H11N5
Targets
5-HT3 receptor: 3 μM (EC50)
Solubility
DMSO: 34 mg/mL (191.86 mM); Water: 34 mg/mL (191.86 mM); Ethanol: 16 mg/mL
Applications
Phenylbiguanide can be used for research on gut motility, visceral sensation, and other aspects of gastrointestinal function.
