Properties
Description
FK866, soluble in ethanol and insoluble in water and DMSO, impedes the activity of phosphorylases, which play a crucial role in breaking down glycogen into glucose-1-phosphate. It targets NMPRTase.
Molecular Formula
C24H29N3O2
Targets
nMPRTase: 0.09 nM
Solubility
DMSO: Insoluble; Water: Insoluble; Ethanol: 77 mg/mL (196.67 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
FK866 is used to inhibit nicotinamide phosphoribosyltransferase, impacting cellular NAD levels and used in cancer and metabolic disorder research.
