Properties
Description
Tipiracil, soluble in DMSO and water and insoluble in ethanol, impedes the activity of phosphorylases, which play a crucial role in breaking down glycogen into glucose-1-phosphate.
Molecular Formula
C9H12Cl2N4O2
Solubility
DMSO: 7 mg/mL (25.08 mM); Water: 50 mg/mL (179.13 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Tipiracil is a phosphorylase inhibitor employed to potentiate chemotherapy efficacy by inhibiting thymidine phosphorylase, reducing drug degradation.