PI3Kγ inhibitor 3, Purity ≥98%

Synonym: 2132961-46-5; AZD3458; CHEMBL4126156; AZD-3458; N-[5-[2-[(1S)-1-cyclopropylethyl]-7-methylsulfonyl-1-oxo-3H-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]acetamide; PI3K inhibitor

CAS Number: 2132961-46-5
Compound CID: 134611894

Product Size

1 mg; 5 mg; 10 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PI3Kγ inhibitor 3 is a potent compound that inhibits PI3 kinase activity. It targets PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ, PI3KC2α, PI3KC2β, PI3KC2γ, and PI3KC3.

Molecular Weight

433.54

Molecular Formula

C₂₀H₂₃N₃O₄S₂

Targets

PI3Kα: 5.1 (pIC₅₀); PI3Kβ: 4.5 (pIC₅₀); PI3Kδ: 6.5 (pIC₅₀); PI3Kγ: 9.1 (pIC₅₀); PI3KC2α: 5 (pIC₅₀); PI3KC2β: 7.5 (pIC₅₀); PI3KC2γ: 5.5 (pIC₅₀); PI3KC3: 5.1 (pIC₅₀)

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

PI3Kγ inhibitor 3 is applied in research on cellular signaling and immune responses.

Storage

Store at -20ºC.