PI3K inhibitor Alpelisib hydrochloride, Purity ≥98%

Synonym: 1584128-91-5; BYL-719 hydrochloride; BYL 719; BYL719; PI3K inhibitor

Product Size

1 mg; 5 mg; 10 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Alpelisib hydrochloride is a potent compound that inhibits PI3 kinase activity. It targets p110α, p110α-E545K, p110α-H1047R, PI3Kβ, PI3Kδ, and PI3Kγ.

Molecular Weight

477.93

Molecular Formula

C₁₉H₂₃ClF₃N₅O₂S

Targets

p110α: 5 nM; p110α-E545K: 4 nM; p110α-H1047R: 4 nM; PI3Kβ: 1200 nM; PI3Kδ: 290 nM; PI3Kγ: 250 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

Alpelisib hydrochloride is used to explore its efficacy as a PI3Kα inhibitor in the context of understanding and treating PI3Kα-driven cancers.