Properties
Description
AMG319, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Formula
C21H16FN7
Targets
PI3Kα: 33 μM; PI3Kβ: 2.7 μM; PI3Kδ: 18 μM; PI3Kγ: 850 μM
Solubility
DMSO: 72 mg/mL (186.82 mM); Water: Insoluble; Ethanol: 72 mg/mL (186.82 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
AMG319 is employed in research focusing on its role as a PI3K delta inhibitor, particularly for investigating its therapeutic potential in hematological malignancies and inflammatory conditions.
