Properties
Description
AS-252424, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets Casein kinase 2, Casein Kinase 2, and PI3Kγ.
Molecular Formula
C14H8FNO4S
Targets
Casein kinase 2: 20 nM; Casein Kinase 2: 935 nM; PI3Kγ: 33 nM
Solubility
DMSO: 57 mg/mL (186.71 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
AS-252424 is used to investigate its effects as a selective PI3K γ inhibitor, providing insights into the role of PI3K γ in immune response and inflammation.
