Properties
Description
AS-604850, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kα, PI3Kγ, and PI3Kγ.
Molecular Formula
C11H5F2NO4S
Targets
PI3Kα: 4.5 μM; PI3Kγ: 0.25 μM; PI3Kγ: 0.18 μM (Ki)
Solubility
DMSO: 49 mg/mL (171.79 mM); Water: Insoluble; Ethanol: 4 mg/mL (14.02 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
AS-604850 is utilized in research as a PI3K γ inhibitor, aiding in the study of PI3K γ signaling in immune cells and its potential in treating inflammation and cancer.
