Properties
Description
AS-605240, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Formula
C12H7N3O2S
Targets
PI3Kα: 60 nM; PI3Kβ: 270 nM; PI3Kδ: 300 nM; PI3Kγ: 8 nM
Solubility
DMSO: 0.38 mg/mL (1.47 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AS-605240 serves as a selective PI3K γ inhibitor in research, helping to unravel the PI3K γ pathway and its implications in immunity and cancer.
