Properties
Description
AZD6482, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets DNA-PK, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Formula
C22H24N4O4
Targets
DNA-PK: 420 nM; PI3Kα: 870 nM; PI3Kβ: 10 nM; PI3Kδ: 80 nM; PI3Kγ: 1090 nM
Solubility
DMSO: 74 mg/mL (181.16 mM); Water: Insoluble; Ethanol: 9 mg/mL (22.03 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
AZD6482 is used to study its effects as a selective PI3K β inhibitor, pertinent in investigating thrombosis and cancer where PI3K β signaling plays a crucial role.
