PI3K inhibitor AZD6482, Purity ≥98%

Synonym: 1173900-33-8; AZD-6482; PI3K inhibitor

CAS Number: 1173900-33-8
Compound CID: 44137675

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AZD6482, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets DNA-PK, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.

Molecular Weight

408.5

Molecular Formula

C₂₂H₂₄N₄O₄

Targets

DNA-PK: 420 nM; PI3Kα: 870 nM; PI3Kβ: 10 nM; PI3Kδ: 80 nM; PI3Kγ: 1090 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 74 mg/mL (181.16 mM); Water: Insoluble; Ethanol: 9 mg/mL (22.03 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

AZD6482 is used to study its effects as a selective PI3K β inhibitor, pertinent in investigating thrombosis and cancer where PI3K β signaling plays a crucial role.