PI3K inhibitor BAY 80-6946, Purity ≥98%

Synonym: 1032568-63-0; BAY80-6946; BAY806946; Copanlisib; PI3K inhibitor

CAS Number: 1032568-63-0
Compound CID: 135565596

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BAY 80-6946, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets mTOR, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.

Molecular Weight

480.2

Molecular Formula

C₂₃H₂₈N₈O₄

Targets

mTOR: 45 nM; PI3Kα: 0.5 nM; PI3Kβ: 3.7 nM; PI3Kδ: 0.7 nM; PI3Kγ: 6.4 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: Insoluble; Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

BAY 80-6946, also known as copanlisib, is studied for its selective inhibition of PI3K α and δ isoforms, relevant for treating hematological malignancies and solid tumors.