Properties
Description
BYL719, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kα.
Molecular Formula
C19H22F3N5O2S
Solubility
DMSO: 77 mg/mL (174.41 mM); Water: Insoluble; Ethanol: 2 mg/mL (4.53 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
BYL719, also known as alpelisib, is used to investigate its specific inhibition of PI3K α, important in targeting PI3K α-dependent cancers.