Properties
Description
CH5132799, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kβ, PI3Kγ, C2α, C2β, mTOR, PI3Kα, PI3Kδ, and Vps34.
Molecular Formula
C15H19N7O3S
Targets
PI3Kβ: 0.12 μM; PI3Kγ: 1.6 μM; C2α: >10 μM; C2β: 5.3 μM; mTOR: 1.6 μM; PI3Kα: 14 nM; PI3Kδ: 0.50 μM; Vps34: >10 μM
Solubility
DMSO: 12 mg/mL (31.79 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
CH5132799 can be used to study the inhibition of PI3K and mTOR signaling pathways in cancer cells.
