Properties
Description
CZC24832, soluble in warmed DMSO and insoluble in water and ethanol, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Formula
C15H17FN6O2S
Targets
PI3Kβ: 1.1 μM; PI3Kδ: 8.2 μM; PI3Kγ: 27 μM
Solubility
Warmed DMSO: 5 mg/mL (13.72 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
CZC24832 can be used to study the inhibition of PI3Kγ specifically, which is involved in inflammatory responses.