Properties
Description
CZC24832, soluble in warmed DMSO and insoluble in water and ethanol, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Formula
C15H17FN6O2S
Targets
PI3Kβ: 1.1 μM; PI3Kδ: 8.2 μM; PI3Kγ: 27 μM
Solubility
Warmed DMSO: 5 mg/mL (13.72 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
CZC24832 can be used to study the inhibition of PI3Kγ specifically, which is involved in inflammatory responses.