PI3K inhibitor ETP-46464, Purity ≥98%

Synonym: 1345675-02-6; ETP46464; ETP 46464; PI3K inhibitor

CAS Number: 1345675-02-6
Compound CID: 72199292

Product Size

10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ETP-46464, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets ATM, ATR, DNA-PK, mTOR, and PI3Kα.

Molecular Weight

470.52

Molecular Formula

C₃₀H₂₂N₄O₂

Targets

ATM: 545 nM; ATR: 14 nM; DNA-PK: 36 nM; mTOR: 0.6 nM; PI3Kα: 170 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 6 mg/mL (12.75 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

ETP-46464 can be used to explore the dual inhibition of PI3K/mTOR for potential anticancer therapy.