PI3K inhibitor GDC-0326, Purity ≥98%

Synonym: 1282514-88-8; GDC0326; GDC 0326; PI3K inhibitor

CAS Number: 1282514-88-8
Compound CID: 58204997

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GDC-0326, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.

Molecular Weight

382.42

Molecular Formula

C₁₉H₂₂N₆O₃

Targets

PI3Kα: 0.2 nM (Ki); PI3Kβ: 26.6 nM (Ki); PI3Kδ: 4 nM (Ki); PI3Kγ: 10.2 nM (Ki)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 72 mg/mL (188.27 mM); Water: Insoluble; Ethanol: 18 mg/mL (47.07 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

GDC-0326 can be employed to study PI3Kα inhibition and its effects on cancer cell proliferation and survival.