PI3K inhibitor GDC-0941, Purity ≥98%

Synonym: 957054-30-7; GDC0941; Pictilisib; PI3K inhibitor

CAS Number: 957054-30-7
Compound CID: 17755052

Product Size

5 mg; 10 mg; 50 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GDC-0941, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets p110β, p110δ, C2β, DNA-PK, mTOR, p110α, p110γ, and Vps34.

Molecular Weight

513.6

Molecular Formula

C₂₃H₂₇N₇O₃S₂

Targets

p110β: 33 nM; p110δ: 3 nM; C2β: 0.67 μM; DNA-PK: 1.23 μM; mTOR: 0.58 μM; p110α: 3 nM; p110γ: 75 nM; Vps34: >10 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 40 mg/mL (77.87 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

GDC-0941 aids in researching the inhibition of all class I PI3K isoforms, specifically in cancer therapy studies.