PI3K inhibitor GDC-0980, Purity ≥98%

Synonym: 1032754-93-0; GDC0980; Apitolisib; RG7422; PI3K inhibitor

CAS Number: 1032754-93-0
Compound CID: 25254071

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GDC-0980, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets mTOR, p110α, p110β, p110δ, and p110γ.

Molecular Weight

498.6

Molecular Formula

C₂₃H₃₀N₈O₃S

Targets

mTOR: 17 nM (Ki app); p110α: 5 nM; p110β: 27 nM; p110δ: 7 nM; p110γ: 14 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 20 mg/mL (40.11 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

GDC-0980 can be used to study dual PI3K/mTOR inhibition in cancer cells.