PI3K inhibitor GNE 477, Purity ≥98%

Synonym: 1032754-81-6; GNE-477; GNE477; PI3K inhibitor

Product Size

2 mg; 5 mg; 10 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GNE 477, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets mTOR and PI3Kα.

Molecular Weight

504.64

Molecular Formula

C₂₁H₂₈N₈O₃S₂

Targets

mTOR: 21 nM (Ki); PI3Kα: 4 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 24 mg/mL (47.56 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

GNE 477 can be used to investigate the inhibition of PI3K/mTOR pathways in cancer research.