PI3K inhibitor GNE-493, Purity ≥98%

Synonym: 1033735-94-2; GNE493; GNE 493; PI3K inhibitor

CAS Number: 1033735-94-2
Compound CID: 25242324

Product Size

10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GNE-493, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets mTOR, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.

Molecular Weight

372.44

Molecular Formula

C₁₇H₂₀N₆O₂S

Targets

mTOR: 30 nM; PI3Kα: 3.4 nM; PI3Kβ: 12 nM; PI3Kδ: 16 nM; PI3Kγ: 16 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 63 mg/mL (169.15 mM); Water: Insoluble; Ethanol: 1 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

GNE-493 can be used to explore its properties as a dual PI3K/mTOR inhibitor in cancer studies.

Storage

Store at -20ºC.