PI3K inhibitor GNE-493, Purity ≥98%

Cat. No.: X24-05-ZQ021

PI3K inhibitor GNE-493, Purity ≥98%

Synonym: 1033735-94-2; GNE493; GNE 493; PI3K inhibitor

  • CAS Number: 1033735-94-2
  • Compound CID: 25242324
Product Size
10 mg; 25 mg; 50 mg
Price
Datasheet
MSDS
Properties
Description
GNE-493, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets mTOR, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Weight
372.44
Molecular Formula
C17H20N6O2S
Targets
mTOR: 30 nM; PI3Kα: 3.4 nM; PI3Kβ: 12 nM; PI3Kδ: 16 nM; PI3Kγ: 16 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 63 mg/mL (169.15 mM); Water: Insoluble; Ethanol: 1 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
GNE-493 can be used to explore its properties as a dual PI3K/mTOR inhibitor in cancer studies.
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