PI3K inhibitor GSK1059615, Purity ≥98%

Synonym: 958852-01-2; GSK-1059615; PI3K inhibitor

CAS Number: 958852-01-2
Compound CID: 23582824

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK1059615, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets mTOR, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.

Molecular Weight

333.4

Molecular Formula

C₁₈H₁₁N₃O₂S

Targets

mTOR: 12 nM; PI3Kα: 0.4 nM; PI3Kβ: 0.6 nM; PI3Kδ: 2 nM; PI3Kγ: 5 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 2 mg/mL (5.99 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

GSK1059615 can be used to examine the inhibition of PI3K/mTOR signaling in cancer research.