Properties
Description
GSK1059615, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets mTOR, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Formula
C18H11N3O2S
Targets
mTOR: 12 nM; PI3Kα: 0.4 nM; PI3Kβ: 0.6 nM; PI3Kδ: 2 nM; PI3Kγ: 5 nM
Solubility
DMSO: 2 mg/mL (5.99 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
GSK1059615 can be used to examine the inhibition of PI3K/mTOR signaling in cancer research.
