PI3K inhibitor IC-87114, Purity ≥98%

Synonym: 371242-69-2; IC-87114; IC87114; 2-((6-Amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one; IC 87114; PI3K inhibitor

CAS Number: 371242-69-2
Compound CID: 9908783

Product Size

5 mg; 10mg; 25 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

IC-87114, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kβ, PI3Kδ, and PI3Kγ.

Molecular Weight

397.4

Molecular Formula

C₂₂H₁₉N₇O

Targets

PI3Kβ: 75 μM; PI3Kδ: 0.5 μM; PI3Kγ: 29 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 0.62 mg/mL (1.56 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

IC-87114 is employed to investigate PI3Kδ inhibition and its effects on immune cell function.