Properties
Description
IPI-3063, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets p110α, p110β, p110δ, and p110γ.
Molecular Formula
C25H25N7O2
Targets
p110α: 1170 nM; p110β: 1508 nM; p110δ: 2.5 nM; p110γ: 2187 nM
Solubility
DMSO: 83 mg/mL (182.21 mM); Water: Insoluble; Ethanol: 11 mg/mL (24.15 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
IPI-3063 serves primarily in the study of selective PI3Kδ inhibition, relevant in B-cell malignancies.
