Properties
Description
IPI-549, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kα, PI3Kβ, and PI3Kγ.
Molecular Formula
C30H24N8O2
Targets
PI3Kα: 3.2 μM; PI3Kβ: 3.5 μM; PI3Kγ: 16 μM
Solubility
DMSO: 87 mg/mL (164.6 mM); Water: Insoluble; Ethanol: 7 mg/mL (13.24 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
IPI-549 helps in investigating PI3Kγ inhibition’s role in tumor microenvironment and immune responses.
