PI3K inhibitor IPI-549, Purity ≥98%

Synonym: 1693758-51-8; IPI549; IPI 549; PI3K inhibitor

CAS Number: 1693758-51-8
Compound CID: 91933883

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

IPI-549, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kα, PI3Kβ, and PI3Kγ.

Molecular Weight

528.56

Molecular Formula

C₃₀H₂₄N₈O₂

Targets

PI3Kα: 3.2 μM; PI3Kβ: 3.5 μM; PI3Kγ: 16 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 87 mg/mL (164.6 mM); Water: Insoluble; Ethanol: 7 mg/mL (13.24 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

IPI-549 helps in investigating PI3Kγ inhibition’s role in tumor microenvironment and immune responses.