Properties
Description
Leniolisib, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets DNA-PK, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Formula
C21H25F3N6O2
Targets
DNA-PK: 880 nM; PI3Kα: 280 nM; PI3Kβ: 480 nM; PI3Kδ: 11 nM; PI3Kγ: 2.57 nM
Solubility
DMSO: 81 mg/mL (179.81 mM); Water: Insoluble; Ethanol: 12 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Leniolisib aids in studying the selective PI3Kδ inhibition relevant to immune disorders.
