PI3K inhibitor Leniolisib, Purity ≥98%

Synonym: 1354690-24-6; CDZ-173; CDZ 173; CDZ173; PI3K inhibitor

CAS Number: 1354690-24-6
Compound CID: 57495353

Product Size

2 mg; 5 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Leniolisib, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets DNA-PK, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.

Molecular Weight

450.46

Molecular Formula

C₂₁H₂₅F₃N₆O₂

Targets

DNA-PK: 880 nM; PI3Kα: 280 nM; PI3Kβ: 480 nM; PI3Kδ: 11 nM; PI3Kγ: 2.57 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 81 mg/mL (179.81 mM); Water: Insoluble; Ethanol: 12 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

Leniolisib aids in studying the selective PI3Kδ inhibition relevant to immune disorders.