PI3K inhibitor MLN1117, Purity ≥98%

Synonym: 1268454-23-4; Serabelisib; INK1117; INK-1117; INK 1117; MLN 1117; MLN-1117; TAK-117; TAK 117; TAK117; PI3K inhibitor

CAS Number: 1268454-23-4
Compound CID: 70798655

Product Size

10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

MLN1117, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets mTOR, p110α, p110β, p110δ, and p110γ.

Molecular Weight

363.13

Molecular Formula

C₁₉H₁₇N₅O₃

Targets

mTOR: 1670 nM; p110α: 15 nM; p110β: 4500 nM; p110δ: 13900 nM; p110γ: 1900 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 15 mg/mL (41.28 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

MLN1117 serves to explore PI3Kα inhibition and its role in cancer treatment.