PI3K inhibitor MLN1117, Purity ≥98%

Synonym: 1268454-23-4; Serabelisib; INK1117; INK-1117; INK 1117; MLN 1117; MLN-1117; TAK-117; TAK 117; TAK117; PI3K inhibitor

CAS Number: 1268454-23-4
Compound CID: 70798655

Product Size

10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

MLN1117, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets mTOR, p110α, p110β, p110δ, and p110γ.

Molecular Weight

363.13

Molecular Formula

C₁₉H₁₇N₅O₃

Targets

mTOR: 1670 nM; p110α: 15 nM; p110β: 4500 nM; p110δ: 13900 nM; p110γ: 1900 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 15 mg/mL (41.28 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

MLN1117 serves to explore PI3Kα inhibition and its role in cancer treatment.

Storage

Store at -20ºC.