PI3K inhibitor NVP-BGT226, Purity ≥98%

Synonym: 1245537-68-1; NVPBGT226; BGT226; BGT-226; PI3K inhibitor

CAS Number: 1245537-68-1
Compound CID: 57336745

Product Size

5 mg; 10 mg; 50 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NVP-BGT226, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets mTOR, PI3Kα, PI3Kβ, and PI3Kγ.

Molecular Weight

650.6

Molecular Formula

C₂₈H₂₅F₃N₆O₂.C₄H₄O₄

Targets

mTOR; PI3Kα: 4 nM; PI3Kβ: 63 nM; PI3Kγ: 38 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 27 mg/mL (41.5 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

NVP-BGT226 can be used to study PI3K/mTOR pathway inhibition in cancer research.