PI3K inhibitor NVP-BKM120 hydrochloride, Purity ≥98%

Synonym: 1312445-63-8; BKM-120 hydrochloride; BKM120 hydrochloride; BKM 120 hydrochloride; PI3K inhibitor

CAS Number: 1312445-63-8
Compound CID: 66577015

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NVP-BKM120 hydrochloride is a potent compound that inhibits PI3 kinase activity. It targets mTOR, p110α, p110α-E545K, p110α-H1047R, p110β, p110δ, p110γ, and Vps34.

Molecular Weight

446.85

Molecular Formula

C₁₈H₂₁F₃N₆O₂.HCl

Targets

mTOR: 4.6 μM; p110α: 52 μM; p110α-E545K: 4.6 μM; p110α-H1047R: 99 nM; p110β: 166 nM; p110δ: 116 nM; p110γ: 262 μM; Vps34: 2.4 μM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

NVP-BKM120 hydrochloride targets PI3K for studying cancer cell proliferation and survival.