Properties
Description
ON 146040 is a potent compound that inhibits PI3 kinase activity. It targets PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Formula
C24H23N7O3S
Targets
PI3Kα: 14 nM; PI3Kβ: 3 nM; PI3Kδ: 20 nM; PI3Kγ: 1 nM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
ON 146040 can be applied to investigate PI3K/AKT/mTOR signaling pathways in cancer.
